Incidence and outcome of lung involvement in IgG4-related autoimmune pancreatitis

Respirology. 2015 Oct;20(7):1142-4. doi: 10.1111/resp.12599. Epub 2015 Jul 17.

Abstract

We evaluated the incidence and outcome of lung involvement in 35 patients with autoimmune pancreatitis (AIP). Our results indicate that lung involvement is commonly observed in AIP (40%). In addition, corticosteroid treatment improved the lung lesions and appeared to reduce the probability of relapse compared with pancreatic lesions (0% vs 36%). This is the first report to assess the long-term outcome of lung involvement in AIP (52 ± 33 months).

Keywords: autoimmune pancreatitis; immunoglobulin G4; immunoglobulin G4-related disease; immunoglobulin G4-related lung disease; type 1 autoimmune pancreatitis.

Publication types

  • Letter

MeSH terms

  • Aged
  • Autoimmune Diseases* / complications
  • Autoimmune Diseases* / drug therapy
  • Early Medical Intervention
  • Female
  • Glucocorticoids / therapeutic use*
  • Humans
  • Immunoglobulin G / immunology*
  • Incidence
  • Lung Diseases* / complications
  • Lung Diseases* / diagnosis
  • Lung Diseases* / drug therapy
  • Lung Diseases* / epidemiology
  • Lung Diseases* / immunology
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care
  • Pancreatitis* / complications
  • Pancreatitis* / drug therapy
  • Pancreatitis* / immunology
  • Prognosis

Substances

  • Glucocorticoids
  • Immunoglobulin G