Impaired response inhibition in juvenile delinquents with antisocial personality characteristics: A preliminary ERP study in a Go/Nogo task

Muzhen Guan; Yang Liao; Huijuan Ren; Xiuchao Wang; Qun Yang; Xufeng Liu; Wei Wang

doi:10.1016/j.neulet.2015.06.062

Impaired response inhibition in juvenile delinquents with antisocial personality characteristics: A preliminary ERP study in a Go/Nogo task

Neurosci Lett. 2015 Aug 31:603:1-5. doi: 10.1016/j.neulet.2015.06.062. Epub 2015 Jul 17.

Authors

Muzhen Guan¹, Yang Liao¹, Huijuan Ren¹, Xiuchao Wang¹, Qun Yang¹, Xufeng Liu², Wei Wang³

Affiliations

¹ Department of Psychology, Fourth Military Medical University, Xi'an, China.
² Department of Psychology, Fourth Military Medical University, Xi'an, China. Electronic address: [email protected].
³ Department of Psychology, Fourth Military Medical University, Xi'an, China. Electronic address: [email protected].

PMID: 26189594
DOI: 10.1016/j.neulet.2015.06.062

Abstract

The present study explored the time course of response inhibition function in juvenile delinquents with antisocial personality characteristics (JDAP) by recording the event-related potentials in a Go/Nogo task. Compared to healthy participants, JDAP participants showed similar performance to controls for the Go trails, but worse performance for the Nogo trails. Both N2nogo and P3nogo components showed reduction of the amplitudes in JDAP participants, reflecting the early stage of associated with conflict monitoring and the late stage of inhibition processing, respectively. These data suggest that JDAP participants exhibited impaired response inhibition function.

Keywords: Antisocial personality disorder; Event- related potentials; Go/Nogo task; Response inhibition.

MeSH terms

Adolescent
Antisocial Personality Disorder / psychology*
Evoked Potentials*
Humans
Inhibition, Psychological*
Juvenile Delinquency / psychology*
Male
Reaction Time