Of 304 consecutive percutaneous transluminal coronary angioplasties (PTCA) performed between March 86 and March 88, 61 patients were 65 years or older. The indications for PTCA were: stable angina, unstable angina and acute myocardial infarction with suitable anatomy. In elderly patients, the female sex, and the calcific deposits, were more frequent than in the younger group (p less than 0.0001). Primary success was achieved in 82%, vs 88% in patients younger than 65 years; complications and mortality were also statistically irrelevant between the two groups. Late clinical follow-up ranging from 3 to 36 months (mean 10) showed that symptomatic improvement was achieved in 86% of elderly patients in whom PTCA was successful (vs 80% in the younger group). These data support the safety and clinical effectiveness of PTCA in elderly symptomatic patients with suitable anatomy.