Abstract
Ferrocenes represent an interesting group of drugs with potential antitumor properties. Moreover, their electronic properties make them suitable for electrochemical studies. We determined an uptake of a novel ferrocene derivative in low μM concentrations by selected cancer cell lines and showed its localization predominantly in cytoplasm, using glassy carbon electrodes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / analysis*
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Antineoplastic Agents / pharmacology
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Cell Line, Tumor
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Cell Survival / drug effects
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Electrochemical Techniques*
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Electrodes
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Ferrous Compounds / chemistry*
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Ferrous Compounds / pharmacology
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Humans
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MCF-7 Cells
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Metallocenes
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Reactive Oxygen Species / chemistry
Substances
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Antineoplastic Agents
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Ferrous Compounds
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Metallocenes
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Reactive Oxygen Species
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ferrocene