IgG4-Related Tubulointerstitial Nephritis Pattern in 18F-FDG PET/CT

Clin Nucl Med. 2015 Oct;40(10):808-9. doi: 10.1097/RLU.0000000000000899.

Abstract

A 17-year-old adolescent girl was admitted with chronic arthralgia, Raynaud phenomenon, pericarditis, and evidences of chronic diffuse inflammation. F-FDG PET/CT scan was performed to search systemic vasculitis and showed diffuse moderate uptake in the kidneys. We suggested the existence of a nephritis, but the ultrasonography result was normal, and no treatment was introduced. Another F-FDG PET/CT scan was performed 7 months later to explore abdominal pain. It showed again diffuse intense uptake in both kidneys. A proteinuria was highlighted, and renal biopsy allowed to diagnose IgG4-related disease.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Immunoglobulin G / immunology*
  • Multimodal Imaging*
  • Nephritis, Interstitial / diagnostic imaging*
  • Nephritis, Interstitial / immunology
  • Positron-Emission Tomography*
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed*

Substances

  • Immunoglobulin G
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18