MB4-2 breakpoint in MMSET combined with del(17p) defines a subset of t(4;14) multiple myeloma with very poor prognosis

Haematologica. 2015 Nov;100(11):e471-4. doi: 10.3324/haematol.2015.127001. Epub 2015 Jul 23.

¹ Immuno-Hematology, Saint-Louis Hospital, Paris, France Université Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM UMR 1126 Institut Universitaire d'Hématologie, Paris, France.
² Université Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM UMR 1126 Institut Universitaire d'Hématologie, Paris, France.
³ Biological Hematology, Saint-Louis Hospital, Paris, France.
⁴ Hematology, Avicenne Hospital, Bobigny, France.
⁵ Hematology, Henri Mondor Hospital, Creteil, France.
⁶ Hematology, Pitie Salpetriere Hospital, Paris, France.
⁷ Hematology, Necker Hospital, Paris, France.
⁸ Hematology, Cochin Hospital, Paris, France.
⁹ Hematology, Caen Hospital, Paris, France.
¹⁰ Biostatistics, Saint-Louis Hospital, Paris, France.
¹¹ Biological Hematology, Purpan Hospital, Toulouse, France.
¹² University Hospital, Nantes, France.
¹³ Immuno-Hematology, Saint-Louis Hospital, Paris, France Université Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM UMR 1126 Institut Universitaire d'Hématologie, Paris, France [email protected].

No abstract available

Keywords: MB4 breakpoint; MMSET; heterogeneity; prognostic factor; t(4/14) translocation.

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