Increased values of the circulating PDGFβ sustains the "withdrawal syndrome" after tyrosine kinase inhibitor discontinuation in patients affected by chronic myeloid leukemia

Blood Cells Mol Dis. 2015 Oct;55(3):211-2. doi: 10.1016/j.bcmd.2015.06.010. Epub 2015 Jun 23.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Female
  • Humans
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / blood
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy*
  • Male
  • Middle Aged
  • Protein Kinase Inhibitors / therapeutic use*
  • Protein-Tyrosine Kinases / antagonists & inhibitors*
  • Proto-Oncogene Proteins c-sis / metabolism*
  • Receptor, Platelet-Derived Growth Factor beta / blood*
  • Substance Withdrawal Syndrome / blood*
  • Substance Withdrawal Syndrome / etiology

Substances

  • Antineoplastic Agents
  • Protein Kinase Inhibitors
  • Proto-Oncogene Proteins c-sis
  • Protein-Tyrosine Kinases
  • Receptor, Platelet-Derived Growth Factor beta