Thrombocytopenic Purpura Associated with Dietary Supplements Containing Citrus Flavonoids

Therapie. 2015 Nov-Dec;70(6):555-6. doi: 10.2515/therapie/2015050. Epub 2015 Aug 4.

Abstract

We report a case of thrombocytopenic purpura associated with the intake of two dietary supplements containing mainly citrus flavonoids. This is the first case to be notified to the French Agency for Food, Environmental and Occupational Health Safety (ANSES). It addresses the importance of an accurate medication history interview for each patient.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adjuvants, Immunologic / adverse effects*
  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Obesity Agents / adverse effects*
  • Citrus / chemistry*
  • Dietary Supplements / adverse effects*
  • Flavanones / adverse effects*
  • Flavones / adverse effects*
  • Hesperidin / adverse effects
  • Hesperidin / analogs & derivatives*
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Male
  • Middle Aged
  • Nonprescription Drugs / adverse effects*
  • Platelet Transfusion
  • Purpura, Thrombocytopenic / chemically induced*
  • Purpura, Thrombocytopenic / therapy

Substances

  • Adjuvants, Immunologic
  • Adrenal Cortex Hormones
  • Anti-Obesity Agents
  • Flavanones
  • Flavones
  • Immunoglobulins, Intravenous
  • Nonprescription Drugs
  • Hesperidin
  • tangeretin
  • naringin
  • neohesperidin