Abstract
Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cell Line, Tumor
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Cysteine / analysis*
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Fluorescent Dyes / chemistry*
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Glutathione / analysis
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HeLa Cells
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Hep G2 Cells
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Homocysteine / analysis
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Humans
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Mice
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Microscopy, Fluorescence, Multiphoton / methods
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Neoplasms / chemistry*
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Neoplasms / pathology*
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Optical Imaging / methods*
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Spectrometry, Fluorescence
Substances
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Fluorescent Dyes
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Homocysteine
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Glutathione
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Cysteine