Change isn't always better

Elife. 2015 Aug 14:4:e10054. doi: 10.7554/eLife.10054.

Authors

Heather Schofield¹, Marina Pasca di Magliano²

Affiliations

¹ Program in Cell and Molecular Biology and the Medical Scientist Training Program, University of Michigan, Ann Arbor, United States.
² Program in Cell and Molecular Biology, Department of Surgery and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, United States.

Abstract

Maintaining the identity of acinar cells in the pancreas could help to prevent the development of pancreatic cancer.

Keywords: developmental biology; differentiation; human; human biology; medicine; mouse; pancreatic cancer; pancreatitis; stem cells.

Publication types

Comment

MeSH terms

Acinar Cells / physiology*
Adenocarcinoma / pathology*
Animals
Carcinoma, Pancreatic Ductal / pathology*
Cell Transdifferentiation*
Humans
Transcription Factors / analysis*

Substances

Transcription Factors

Grants and funding