Primary pulmonary leiomyosarcoma of lung: An unusual entity with brief review

Indian J Pathol Microbiol. 2015 Jul-Sep;58(3):338-40. doi: 10.4103/0377-4929.162868.

Abstract

Primary pulmonary leiomyosarcomas are rare and diagnostically challenging group of neoplasms approximately constituting 0.2-0.5% of all primary lung malignancies. They originate from the smooth muscle cells of the bronchial wall, blood vessels or from the pulmonary interstitium. Here we present a case of 45 year old male with history of chronic cough, breathlessness and chest pain for few months. Clinical and radiological workup showed a left upper lobe lung mass. Endobronchial ultrasound guided (EUS) needle biopsy of the mass on histopathology confirmed leiomyosarcoma. Further through evaluation ruled out the possibility of metastasis. A final diagnosis of primary leiomyosarcoma of lung was made and patient was planned for surgical management.

Publication types

  • Case Reports

MeSH terms

  • Actins / analysis
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Bronchoscopy
  • Desmin / analysis
  • Histocytochemistry
  • Humans
  • Immunohistochemistry
  • Ki-67 Antigen / analysis
  • Leiomyosarcoma / diagnosis*
  • Leiomyosarcoma / pathology*
  • Lung / pathology*
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / pathology*
  • Male
  • Microscopy
  • Middle Aged
  • Radiography, Thoracic
  • Tomography, X-Ray Computed

Substances

  • Actins
  • Biomarkers, Tumor
  • Desmin
  • Ki-67 Antigen