Evaluation of low-dose cytarabine therapy in myelodysplastic syndromes

Bone Marrow Transplant. 1989 Dec:4 Suppl 3:100.

Abstract

Myelodysplastic syndromes (MDS) are a group of disorders characterised by progressive cytopenias and impaired maturation of haematopoietic cells. It carries a high mortality due to severe infections and/or bleeding, and transformation into acute myeloid leukaemia (AML). Its treatment is largely unsatisfactory except a few favorable reports with low-dose cytarabine therapy, which has recently created a widespread enthusiasm for its use.

MeSH terms

  • Aged
  • Cytarabine / administration & dosage*
  • Drug Evaluation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myelodysplastic Syndromes / drug therapy*

Substances

  • Cytarabine