Stressing about misplaced fat is a key to longevity

Elife. 2015 Aug 19:4:e10161. doi: 10.7554/eLife.10161.

Abstract

The abnormal accumulation of fat increases the lifespans of nematodes that lack sex cells.

Keywords: C. elegans; SKN-1/Nrf; aging; cell biology; chromosomes; fatty acid signaling; genes; germline stem cells; lipid metabolism; proteostasis.

Publication types

  • Comment

MeSH terms

  • Animals
  • Caenorhabditis elegans / physiology*
  • Caenorhabditis elegans Proteins / metabolism*
  • DNA-Binding Proteins / metabolism*
  • Gene Expression Regulation*
  • Germ Cells / physiology*
  • Lipid Metabolism*
  • Transcription Factors / metabolism*

Substances

  • Caenorhabditis elegans Proteins
  • DNA-Binding Proteins
  • Transcription Factors