Relationship between pelvic floor muscle and hormone levels in polycystic ovary syndrome

Neurourol Urodyn. 2016 Sep;35(7):780-5. doi: 10.1002/nau.22817. Epub 2015 Aug 19.

Abstract

Aims: To evaluate the electrical activity of the pelvic floor muscles (PFM) in women with polycystic ovary syndrome.

Methods: Forty-two women with polycystic ovary syndrome (PCOS group) and 13 premenopausal women (control group) were recruited in this cross-sectional study. Total testosterone and estradiol were measured and muscle tone and maximum voluntary contraction (MVC) of PFM were determined by surface electromyography.

Results: There was a difference in muscle tone (PCOS = 59.9 µV and Control group = 25.5 µV; P < 0.0001) and MVC (PCOS = 159.7 µV and Control group = 63.7 µV; P < 0.0002) between groups. The concentration of estradiol and testosterone showed a strong correlation with tone (r = 0.9, r = 0.8 respectively) and MVC (r = 0.9, r = 0.9 respectively) in women with PCOS. The control group exhibited a strong correlation between testosterone and muscle tone (r = 0.9) and MVC (r = 0.9).

Conclusion: Women with PCOS display higher electromyographic values than those in premenopause. Moreover, electrical activity showed a positive relation with estradiol and testosterone concentrations. Although PCOS is a heterogeneous disorder affecting young women, it is suggested that the hyperandrogenic state associated with PCOS is a protective factor for PFM. Neurourol. Urodynam. 35:780-785, 2016. © 2015 Wiley Periodicals, Inc.

Keywords: electromyography; pelvic floor; polycystic ovary syndrome.

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Electromyography
  • Estradiol / blood*
  • Female
  • Humans
  • Muscle Contraction / physiology*
  • Muscle, Skeletal / physiopathology*
  • Overweight / blood
  • Overweight / physiopathology
  • Pelvic Floor / physiopathology*
  • Polycystic Ovary Syndrome / blood
  • Polycystic Ovary Syndrome / physiopathology*
  • Testosterone / blood*
  • Young Adult

Substances

  • Testosterone
  • Estradiol