A case of uncontrolled severe asthma patient with coexisting carcinoid tumor presenting as pneumomediastinum

J Asthma. 2015;52(10):1095-8. doi: 10.3109/02770903.2015.1054402. Epub 2015 Aug 17.

Abstract

Introduction: Patients with inadequately controlled or uncontrolled asthma are at a greater risk of attacks for asthma requiring emergency room visits or hospital admissions. There is a significant correlation between the severity of the disease and the severity of exacerbations. Patients with poorly controlled asthma are at a higher risk for complications.

Case study: We present a 24-year-old aspirin-intolerant, uncontrolled asthma patient with the complication of pneumomediastinum.

Results: Severe symptoms persisted after the resolution of the pneumomediastinum despite intense anti-inflammatory and anti-obstructive therapy. A bronchoscopy revealed an endobronchial lesion and she was diagnosed with a carcinoid tumor.

Conclusion: This case is an example of the importance of re-evaluating asthma patients who do not respond to standard medical treatment. Clinicians should be aware of the complications associated with asthma attacks such as pneumomediastinum and the possibility of a differential diagnosis that worsen asthma symptoms such as a carcinoid tumor.

Keywords: Carcinoid tumor; pneumomediastinum; severe asthma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Asthma / complications*
  • Carcinoid Tumor / diagnosis*
  • Carcinoid Tumor / etiology*
  • Diagnosis, Differential
  • Female
  • Humans
  • Mediastinal Emphysema / diagnosis*
  • Mediastinal Neoplasms / diagnosis*
  • Mediastinal Neoplasms / etiology*
  • Severity of Illness Index