Hemoglobinopathies and Leg Ulcers

Int J Low Extrem Wounds. 2015 Sep;14(3):213-6. doi: 10.1177/1534734615600069. Epub 2015 Aug 20.

Abstract

Major hemoglobinopathies, including sickle cell anemia, are becoming a global health issue. Leg ulcers are the most common cutaneous manifestation of sickle cell disease and an important contributor to morbidity burden in this population. Leg ulcers following sickling disorders are extremely painful, and hard to heal. The clinical evidence for the optimal management of these ulcers is limited. Treating the cause and the strategies to prevent sickling are the mainstay of treatment. The basic principles of wound bed preparation and compression therapy is beneficial in these patients.

Keywords: anemia; hemoglobinopathies; infection; leg ulcer; sickle cell ulcers.

Publication types

  • Editorial

MeSH terms

  • Disease Management
  • Global Health
  • Hemoglobinopathies* / complications
  • Hemoglobinopathies* / epidemiology
  • Hemoglobinopathies* / therapy
  • Humans
  • Leg Ulcer* / epidemiology
  • Leg Ulcer* / etiology
  • Leg Ulcer* / therapy
  • Morbidity / trends
  • Wound Healing