Computed tomography and (18)F-fluorodeoxyglucose positron emission tomography/computed tomography findings in adrenal candidiasis and histoplasmosis: two cases

Clin Imaging. 2015 Nov-Dec;39(6):1115-8. doi: 10.1016/j.clinimag.2015.07.010. Epub 2015 Jul 16.

Abstract

We report the contrast-enhanced computed tomography (CT) and (18)F-fluorodeoxyglucose positron emission tomography findings in adrenal histoplasmosis and candidiasis. Both demonstrated bilateral hypermetabolic heterogeneous adrenal masses with limited wash-out on delayed CT. Adrenal candidiasis has not been previously reported, nor have the CT wash-out findings in either infection. The adrenal imaging findings are indistinguishable from malignancy, which is more common; but in this setting, physicians should be alert to the differential diagnosis of fungal infections, since it can be equally deadly.

Keywords: Adrenal candidiasis; Adrenal histoplasmosis; Bilateral adrenal masses; FDG-PET/CT.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Diseases / diagnostic imaging*
  • Aged
  • Candidiasis / diagnostic imaging*
  • Contrast Media
  • Diagnosis, Differential
  • Fluorodeoxyglucose F18
  • Histoplasmosis / diagnostic imaging*
  • Humans
  • Male
  • Middle Aged
  • Positron-Emission Tomography / methods
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed / methods

Substances

  • Contrast Media
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18