Detection of a new BF F subtype variant by isoelectric focusing

Exp Clin Immunogenet. 1989;6(2):156-61.

Abstract

The paper reports a new BF F variant which was observed in a family, i.e. in the father and in 2 of the 4 children. The variant can only be seen by means of isoelectric focusing and appears as an additional cathodic band of the BF subtype FB. We suggest FB1 as a preliminary name for this variant. The family studied suggested an autosomal-codominant inheritance.

MeSH terms

  • Complement Factor B / classification
  • Complement Factor B / genetics*
  • Complement Factor B / isolation & purification
  • Enzyme Precursors / genetics*
  • Female
  • Genes, Dominant
  • Genetic Variation
  • Humans
  • Isoelectric Focusing
  • Male
  • Pedigree

Substances

  • Enzyme Precursors
  • Complement Factor B