Small intestine dysfunction in Parkinson's disease

J Neural Transm (Vienna). 2015 Dec;122(12):1659-61. doi: 10.1007/s00702-015-1442-0. Epub 2015 Aug 26.

Abstract

The aim of this study was to assess the small bowel transit time in patients with Parkinson's disease (PD). Ten patients with PD with no gastrointestinal complaints and ten healthy control subjects were investigated using single photon emission computed tomography fused with computed tomography after swallowing of a specially prepared capsule containing technetium 99m, which allowed visualization of the passage in the intestines. Preliminary results show that the small intestine passage in PD patients was prolonged compared to controls.

Keywords: Autonomic dysfunction; Parkinson’s disease; Small intestine passage.

MeSH terms

  • Aged
  • Female
  • Humans
  • Intestinal Diseases / complications*
  • Intestinal Diseases / diagnostic imaging
  • Intestinal Diseases / physiopathology*
  • Intestine, Small / diagnostic imaging
  • Intestine, Small / physiopathology*
  • Male
  • Middle Aged
  • Multimodal Imaging
  • Parkinson Disease / complications*
  • Parkinson Disease / diagnostic imaging
  • Parkinson Disease / physiopathology*
  • Radiopharmaceuticals
  • Technetium
  • Time Factors
  • Tomography, Emission-Computed, Single-Photon
  • Tomography, X-Ray Computed

Substances

  • Radiopharmaceuticals
  • Technetium