Use of tumor necrosis factor alpha (TNF α) antagonists in a patient with psoriasis and Chagas disease

Cristián Navarrete-Dechent; Daniela Majerson; Marisa Torres; Daniela Armijo; Mahir Patel; Alan Menter; Claudia de la Cruz

doi:10.1590/abd1806-4841.20153538

Use of tumor necrosis factor alpha (TNF α) antagonists in a patient with psoriasis and Chagas disease

An Bras Dermatol. 2015 May-Jun;90(3 Suppl 1):171-4. doi: 10.1590/abd1806-4841.20153538.

Authors

Cristián Navarrete-Dechent¹, Daniela Majerson¹, Marisa Torres¹, Daniela Armijo¹, Mahir Patel², Alan Menter², Claudia de la Cruz¹

Affiliations

¹ Pontificia Universidad Católica de Chile, Santiago, CL.
² University Medical Center, Dallas, TX, US.

Abstract

There are several studies on the benefits of using TNFα antagonists in the treatment of psoriasis, but few studies addressing the interaction of these drugs with chronic infections. We report the case of a 52-year-old patient diagnosed with psoriasis refractory to traditional systemic agents, who was treated with biologic therapies. After one year of treatment with biologic agents, the patient was diagnosed with Chagas Disease.

Publication types

Case Reports

MeSH terms

Adalimumab / therapeutic use*
Anti-Inflammatory Agents / therapeutic use*
Biological Factors / therapeutic use
Biological Therapy / methods
Chagas Disease / drug therapy*
Humans
Male
Middle Aged
Polymerase Chain Reaction
Psoriasis / drug therapy*
Reproducibility of Results
Treatment Outcome
Tumor Necrosis Factor-alpha / antagonists & inhibitors*

Substances

Anti-Inflammatory Agents
Biological Factors
Tumor Necrosis Factor-alpha
Adalimumab