How should we choose the 'best' embryo? A commentary on behalf of the British Fertility Society and the Association of Clinical Embryologists

Hum Fertil (Camb). 2015 Sep;18(3):156-64. doi: 10.3109/14647273.2015.1072646. Epub 2015 Aug 27.

Abstract

Embryo selection to improve pregnancy rates remains a significant challenge in IVF. Non-invasive and invasive methods of embryo selection include morphological assessment, metabolomics, time-lapse imaging and preimplantation genetic screening. To date, none has been shown conclusively to yield improved implantation and live birth rates. This review summarises current understanding of methods for embryo selection.

Keywords: IVF; embryo viability; human embryo.

MeSH terms

  • Cryopreservation
  • Embryo Implantation / physiology
  • Embryo, Mammalian / anatomy & histology
  • Embryo, Mammalian / physiology*
  • Embryology / methods*
  • Female
  • Fertility
  • Fertilization in Vitro
  • Genetic Testing / methods
  • Humans
  • Practice Guidelines as Topic
  • Pregnancy
  • Pregnancy Rate
  • Preimplantation Diagnosis
  • Single Embryo Transfer / methods
  • Societies, Medical
  • Time-Lapse Imaging
  • United Kingdom