Antibodies for strain 2117-like vesiviruses (caliciviruses) in humans

Barbara Di Martino; Federica Di Profio; Gianvito Lanave; Simona De Grazia; Giovanni M Giammanco; Antonio Lavazza; Canio Buonavoglia; Fulvio Marsilio; Krisztián Bányai; Vito Martella

doi:10.1016/j.virusres.2015.08.016

Antibodies for strain 2117-like vesiviruses (caliciviruses) in humans

Virus Res. 2015 Dec 2:210:279-82. doi: 10.1016/j.virusres.2015.08.016. Epub 2015 Aug 28.

Affiliations

¹ Faculty of Veterinary Medicine, Università degli Studi di Teramo, Italy. Electronic address: [email protected].
² Faculty of Veterinary Medicine, Università degli Studi di Teramo, Italy.
³ Faculty of Veterinary Medicine, Università Aldo Moro di Bari, Valenzano, Italy.
⁴ Department of Scienze per la Promozione della Salute "G. D'Alessandro", Università degli Studi di Palermo, Italy.
⁵ Centro di Referenza Nazionale per le Malattie Virali dei Lagomorfi, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Italy.
⁶ Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary.

PMID: 26319448
DOI: 10.1016/j.virusres.2015.08.016

Abstract

The vesivirus strain 2117 has been identified as contaminant of bioreactors used for production of human drugs, due to possible contamination of the reagents used for cell cultivation. Using an ELISA assay, antibodies specific for 2117-like viruses were detected in 32/410 (7.8%) human sera, indicating exposure to these viruses.

Keywords: Antibodies; Caliciviruses; Humans; Vesivirus strain 2117.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Antibodies, Viral / blood*
Child
Child, Preschool
Environmental Exposure*
Female
Humans
Infant
Infant, Newborn
Male
Middle Aged
Seroepidemiologic Studies
Vesivirus / immunology*
Young Adult

Substances

Antibodies, Viral