Relative Survival of Breast Cancer Patients in Iran

Asian Pac J Cancer Prev. 2015;16(14):5853-8. doi: 10.7314/apjcp.2015.16.14.5853.

Abstract

Background: The survival rate reflecting prognosis of breast cancer patients is usually estimated based on crude survival methods such as observed and cause-specific. In situations where data are based on population-cancer registries, this method may produce biased estimations. This study therefore aimed to estimate the net survival of breast cancer based on relative survival.

Materials and methods: Data for 622 breast cancer patients diagnosed at the Iran Cancer Institute during 1990-95 and tracked till the end of 2000 were analyzed. For estimation of relative survival, Ederer's second method and SAS (9.1) and STATA (11) software were used.

Results: Three- year relative survivals of 85%, 90%, 80% and 67% were observed for age groups 15-44, 55-59, 60-74, and 75+ years-old, respectively. A relative survival of approximately one was observed for two subsequent years for age-group 45-59 years-old. A value greater than one for two subsequent years of follow-up was observed in the age-group 60-74 years-old.

Conclusions: Tracking the diagnosis of breast cancer, the relative survival decreases as we go to higher age-groups. It is also perceived that through follow-up, relative survival first decreased and then increased a little. The statistical cure point is acceptable for age group 45-59 years-old while for age-groups 15-44 and 60-74 years old is a sign of low quality data for some follow-up intervals.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / epidemiology
  • Breast Neoplasms / mortality*
  • Female
  • Follow-Up Studies
  • Humans
  • Iran / epidemiology
  • Middle Aged
  • Mortality / trends*
  • Prognosis
  • Registries
  • Survival Rate
  • Young Adult