Dopaminergic Therapy for Restless Legs Syndrome/Willis-Ekbom Disease

Rochelle S Zak; Arthur S Walters

doi:10.1016/j.jsmc.2015.05.012

Dopaminergic Therapy for Restless Legs Syndrome/Willis-Ekbom Disease

Sleep Med Clin. 2015 Sep;10(3):279-85, xiii. doi: 10.1016/j.jsmc.2015.05.012. Epub 2015 Jul 14.

Authors

Rochelle S Zak¹, Arthur S Walters²

Affiliations

¹ Sleep Disorders Center, University of California San Francisco, 2330 Post Street, San Francisco, CA 94115, USA. Electronic address: [email protected].
² Department of Neurology, Vanderbilt University Medical Center, 2220 Pierce Avenue, Nashville, TN 37232, USA.

PMID: 26329437
DOI: 10.1016/j.jsmc.2015.05.012

Abstract

Dopaminergic therapies have been a mainstay of restless legs treatment and are endorsed as first-line therapies by multiple professional societies. This article summarizes the differences and similarities among the dopamine agonists with attention to pharmacology, efficacy, side effects, and dosing.

Keywords: Dopamine agonists; Restless legs syndrome; Treatment efficacy; Willis-Ekbom disease.

Publication types

Review

MeSH terms

Dopamine Agonists / administration & dosage*
Dopamine Agonists / adverse effects
Dopamine Agonists / pharmacology
Humans
Restless Legs Syndrome / drug therapy*

Substances

Dopamine Agonists