Short-term exposure to fine and coarse particles and mortality: A multicity time-series study in East Asia

Environ Pollut. 2015 Dec:207:43-51. doi: 10.1016/j.envpol.2015.08.036. Epub 2015 Sep 1.

Abstract

Few studies on size-specific health effects of particulate matter have been conducted in Asia. We examined the association between both fine and coarse particles (PM2.5 and PM10-2.5) and mortality across 11 East Asian cities from 4 countries (Korea, Japan, Taiwan, and China). We performed a two-stage analysis: we generated city-specific estimates using a time-series analysis with a generalized additive model (Quasi-Poisson distribution), and estimated the overall effects by conducting a meta-analysis. Each 10-μg/m(3) increase in PM2.5 (lag01) was associated with an increase of 0.38% (95% confidence interval = 0.21%-0.55%) in all causes mortality, 0.96% (0.46%-1.46%) in cardiovascular mortality, and 1% (0.23%-1.78%) in respiratory mortality. Each 10-μg/m(3) increase in PM10-2.5 (lag01) was associated with cardiovascular mortality (0.69%, [0.05%-1.33%]), although this association attenuated after controlling for other pollutants, especially PM2.5. Increased mortality was associated with increasing PM2.5 and PM10-2.5 concentrations over 11 East Asian cities.

Keywords: Air pollution; Coarse particles; Fine particles; Mortality; Particulate matter.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Air Pollutants / adverse effects*
  • Air Pollutants / analysis
  • Asia, Eastern / epidemiology
  • Cities / epidemiology
  • Environmental Exposure / adverse effects*
  • Environmental Exposure / analysis
  • Humans
  • Models, Theoretical
  • Mortality*
  • Particle Size
  • Particulate Matter / adverse effects*
  • Particulate Matter / analysis
  • Poisson Distribution

Substances

  • Air Pollutants
  • Particulate Matter