A novel RRM2B gene variant associated with Telbivudine-induced mitochondrial myopathy

J Neurol Sci. 2015 Nov 15;358(1-2):481-3. doi: 10.1016/j.jns.2015.08.1550. Epub 2015 Sep 2.
No abstract available

Keywords: Genetics; Mitochondrial disorders; Muscle disease; Toxicology.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antiviral Agents / administration & dosage
  • Antiviral Agents / toxicity*
  • Cell Cycle Proteins / genetics*
  • Female
  • Hepatitis B, Chronic / drug therapy
  • Hepatitis B, Chronic / surgery
  • Humans
  • Liver Transplantation
  • Mitochondrial Myopathies / chemically induced*
  • Mitochondrial Myopathies / genetics*
  • Mutation
  • Ribonucleotide Reductases / genetics*
  • Telbivudine
  • Thymidine / administration & dosage
  • Thymidine / analogs & derivatives*
  • Thymidine / toxicity

Substances

  • Antiviral Agents
  • Cell Cycle Proteins
  • Telbivudine
  • RRM2B protein, human
  • Ribonucleotide Reductases
  • Thymidine