Molecular Assembly of Wheat Gliadins into Nanostructures: A Small-Angle X-ray Scattering Study of Gliadins in Distilled Water over a Wide Concentration Range

J Agric Food Chem. 2015 Oct 7;63(39):8715-21. doi: 10.1021/acs.jafc.5b02902. Epub 2015 Sep 24.

Abstract

Gliadin, one of the major proteins together with glutenin composing gluten, affects the physical properties of wheat flour dough. In this study, nanoscale structures of hydrated gliadins extracted into distilled water were investigated primarily by small-angle X-ray scattering (SAXS) over a wide range of concentrations. Gliadins are soluble in distilled water below 10 wt %. Guinier analyses of SAXS profiles indicate that gliadins are present as monomers together with small amounts of dimers and oligomers in a very dilute solution. The SAXS profiles also indicate that interparticle interference appears above 0.5 wt % because of electrostatic repulsion among gliadin assemblies. Above 15 wt %, gliadins form gel-like hydrated solids. At greater concentrations, a steep upturn appears in the low-q region owing to the formation of large aggregates, and a broad shoulder appears in the middle-q region showing density fluctuation inside. This study demonstrates that SAXS can effectively disclose the nanostructure of hydrated gliadin assemblies.

Keywords: SAXS; gliadin; molecular nanostructures; protein cross-linking; viscoelastic properties; wheat protein.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gliadin / chemistry*
  • Scattering, Small Angle
  • Static Electricity
  • Triticum / chemistry*

Substances

  • Gliadin