High Prevalence of vanM in Vancomycin-Resistant Enterococcus faecium Isolates from Shanghai, China

Antimicrob Agents Chemother. 2015 Dec;59(12):7795-8. doi: 10.1128/AAC.01732-15. Epub 2015 Sep 14.

Abstract

The vanM gene was first found in a vancomycin-resistant Enterococcus faecium (VREm) isolate in Shanghai in 2006. In this study, we found that, in 70 VREm strains isolated in nine Shanghai hospitals from 2006 to 2014, vanM was more prevalent than the vanA gene (64.3% [45/70] versus 35.7% [25/70]). The vanM-type isolates showed similar antimicrobial susceptibility patterns with the vanA types. The vanM-type VREm emerged and disseminated in Shanghai.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • China / epidemiology
  • Cross Infection / epidemiology
  • Cross Infection / microbiology
  • Enterococcus faecium / drug effects*
  • Enterococcus faecium / genetics*
  • Enterococcus faecium / pathogenicity
  • Genes, Bacterial / genetics*
  • Gram-Positive Bacterial Infections / epidemiology*
  • Gram-Positive Bacterial Infections / microbiology*
  • Humans
  • Microbial Sensitivity Tests
  • Prevalence
  • Vancomycin Resistance / genetics*

Substances

  • Anti-Bacterial Agents