Varicella Zoster Virus Cerebellitis Without a Rash in an Immunocompetent 85-Year-Old Patient

Neurologist. 2015 Sep;20(3):44-5. doi: 10.1097/NRL.0000000000000051.

Abstract

Background: Reactivation of the varicella zoster virus (VZV) in adults rarely presents with neurological symptoms without a rash. To our knowledge, so far, only 3 additional cases of VZV cerebellitis, which presented without a rash and were proven by cerebrospinal fluid analysis, have been reported in the literature.

Case report: An immunocompetent 85-year-old patient presented with a new-onset tremor. He had no rash, had a normal brain computed tomography and magnetic resonance imaging, and had minimal cerebrospinal fluid findings. Eventually, he was diagnosed as having varicella zoster virus cerebellitis only on the basis of a virological examination.

Conclusions: The manifestation of a new-onset tremor and gait ataxia should raise a suspicion of cerebellitis caused by VZV, even in the absence of cutaneous manifestations or typical imaging findings.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Cerebellar Ataxia / diagnosis*
  • Cerebellar Ataxia / virology*
  • Exanthema / complications
  • Herpes Zoster / complications*
  • Herpesvirus 3, Human
  • Humans
  • Male