The plasma membrane NADPH oxidase OsRbohA plays a crucial role in developmental regulation and drought-stress response in rice

Physiol Plant. 2016 Apr;156(4):421-43. doi: 10.1111/ppl.12389. Epub 2015 Oct 31.

Abstract

Plasma membrane NADPH oxidases are major producers of reactive oxygen species (ROS) in plant cells under normal growth and stress conditions. In the present study the total activity of rice NADPH oxidases and the transcription of OsRbohA, which encodes an Oryza sativa plasma membrane NADPH oxidase, were stimulated by drought. OsRbohA was expressed in all tissues examined throughout development. Its mRNA was upregulated by a number of factors, including heat, drought, salt, oxidative stress and methyl jasmonate treatment. Compared with wild-type (WT), the OsRbohA-knockout mutant osrbohA exhibited upregulated expression of other respiratory burst oxidase homolog genes and multiple abnormal agronomic traits, including reduced biomass, low germination rate and decreased pollen viability and seed fertility. However, OsRbohA-overexpressing transgenic plants showed no differences in these traits compared with WT. Although osrbohA leaves and roots produced more ROS than WT, the mutant had lesser intracellular ROS. In contrast, OsRbohA-overexpressing transgenic plants exhibited higher ROS production at the intracellular level and in tissues. Ablation of OsRbohA impaired the tolerance of plants to various water stresses, whereas its overexpression enhanced the tolerance. In addition, a number of genes related to energy supply, substrate transport, stress response and transcriptional regulation were differentially expressed in osrbohA plants even under normal growth conditions, suggesting that OsRbohA has fundamental and broad functions in rice. These results indicate that OsRbohA-mediated processes are governed by complex signaling pathways that function during the developmental regulation and drought-stress response in rice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetates / metabolism
  • Cell Membrane / enzymology
  • Cyclopentanes / metabolism
  • Droughts
  • Gene Expression Regulation, Plant*
  • Germination
  • Mutation
  • NADPH Oxidases / genetics
  • NADPH Oxidases / metabolism*
  • Oryza / cytology
  • Oryza / enzymology*
  • Oryza / genetics
  • Oryza / physiology
  • Oxylipins / metabolism
  • Plant Growth Regulators / metabolism
  • Plant Leaves / cytology
  • Plant Leaves / enzymology
  • Plant Leaves / genetics
  • Plant Leaves / physiology
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Plant Roots / cytology
  • Plant Roots / enzymology
  • Plant Roots / genetics
  • Plant Roots / physiology
  • Plants, Genetically Modified
  • Reactive Oxygen Species / metabolism
  • Seedlings / cytology
  • Seedlings / enzymology
  • Seedlings / genetics
  • Seedlings / physiology
  • Signal Transduction*
  • Sodium Chloride / pharmacology
  • Stress, Physiological

Substances

  • Acetates
  • Cyclopentanes
  • Oxylipins
  • Plant Growth Regulators
  • Plant Proteins
  • Reactive Oxygen Species
  • Sodium Chloride
  • methyl jasmonate
  • NADPH Oxidases
  • superoxide-forming enzyme