In this study calculi from human submandibular salivary glands were examined with the method of fluorescence and diffraction of X-rays, as well as the radiocrystallographique method. Beside the already known substances, a significant amount of iodine was found. It is the first time that iodine is found as component of calculi of the human salivary glands. The patients history (thyroid glands etc) didn't give an explanation for the presence of iodine.