Increased expression of E3 ubiquitin ligases targeting p53 in CLL patients with wild-type TP53 exhibits associations with clinical features of the disease

Leuk Lymphoma. 2016;57(6):1471-3. doi: 10.3109/10428194.2015.1096355. Epub 2015 Nov 16.

Authors

Affiliations

¹ a Department of Diagnostic Hematology , Institute of Hematology and Transfusion Medicine , Warsaw , Poland.
² b Department of Hematology , Institute of Hematology and Transfusion Medicine , Warsaw , Poland.
³ c Department of Hematology and Transfusion Medicine , Centre of Postgraduate Medical Education , Warsaw , Poland.

PMID: 26414098
DOI: 10.3109/10428194.2015.1096355

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Disease Progression
Gene Expression Regulation, Leukemic*
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Leukemia, Lymphocytic, Chronic, B-Cell / metabolism*
Leukemia, Lymphocytic, Chronic, B-Cell / mortality
Leukemia, Lymphocytic, Chronic, B-Cell / pathology
Prognosis
Tumor Suppressor Protein p53 / genetics*
Tumor Suppressor Protein p53 / metabolism*
Ubiquitin-Protein Ligases / genetics*
Ubiquitin-Protein Ligases / metabolism*

Substances

Tumor Suppressor Protein p53
Ubiquitin-Protein Ligases