Treatment of Acute Cough Due to the Common Cold: Multi-component, Multi-symptom Therapy is Preferable to Single-Component, Single-Symptom Therapy--A Pro/Con Debate

Lung. 2016 Feb;194(1):15-20. doi: 10.1007/s00408-015-9808-5. Epub 2015 Sep 29.

Abstract

Acute viral upper respiratory tract infection, or, the common cold, affects essentially every human being, and cough is reported as its most frequent associated symptom. Billions of dollars are spent worldwide annually by individuals seeking relief from this multi-symptom syndrome. Thousands of non-prescription, over-the-counter products are available worldwide, aimed at relieving the various bothersome symptoms induced by the common cold. Differences of opinion exist as to whether optimal therapy for cough associated with the common cold consists of multi-component, multi-symptom cough/cold preparations, or, whether single-component medications, aimed at relief of specific symptoms, represent the optimal therapeutic approach. The 5th American Cough Conference, held in Washington, D.C. in June, 2015, provided an ideal forum for discussion and debate of this issue between two internationally recognized experts in the field of the common cold and its treatment.

Keywords: Antitussive; Common cold; Cough; Respiratory tract infection; Viral infection.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Analgesics / therapeutic use
  • Antitussive Agents / therapeutic use
  • Cholinergic Antagonists / therapeutic use
  • Common Cold / complications
  • Common Cold / drug therapy*
  • Cough / drug therapy*
  • Cough / virology
  • Drug Combinations
  • Drug-Related Side Effects and Adverse Reactions
  • Expectorants / therapeutic use
  • Histamine Antagonists / therapeutic use
  • Humans
  • Medication Adherence
  • Nasal Decongestants / therapeutic use

Substances

  • Analgesics
  • Antitussive Agents
  • Cholinergic Antagonists
  • Drug Combinations
  • Expectorants
  • Histamine Antagonists
  • Nasal Decongestants