Approach for classification and taxonomy within family Rickettsiaceae based on the Formal Order Analysis

S Shpynov; N Pozdnichenko; A Gumenuk

doi:10.1016/j.micinf.2015.09.012

Approach for classification and taxonomy within family Rickettsiaceae based on the Formal Order Analysis

Microbes Infect. 2015 Nov-Dec;17(11-12):839-44. doi: 10.1016/j.micinf.2015.09.012. Epub 2015 Sep 28.

Authors

S Shpynov¹, N Pozdnichenko², A Gumenuk²

Affiliations

¹ N.F. Gamaleya FRCEM, Gamaleya Str., 18, Moscow, 123098, Russia. Electronic address: [email protected].
² OmSTU, Omsk, Russia.

PMID: 26423020
DOI: 10.1016/j.micinf.2015.09.012

Abstract

Genome sequences of 36 Rickettsia and Orientia were analyzed using Formal Order Analysis (FOA). This approach takes into account arrangement of nucleotides in each sequence. A numerical characteristic, the average distance (remoteness) - "g" was used to compare of genomes. Our results corroborated previous separation of three groups within the genus Rickettsia, including typhus group, classic spotted fever group, and the ancestral group and Orientia as a separate genus. Rickettsia felis URRWXCal2 and R. akari Hartford were not in the same group based on FOA, therefore designation of a so-called transitional Rickettsia group could not be confirmed with this approach.

Keywords: Average distance (remoteness); Classification; Formal Order Analysis; Genome; Rickettsia; Taxonomy.

MeSH terms

Bacterial Typing Techniques
Genome, Bacterial / genetics*
Orientia tsutsugamushi / classification*
Orientia tsutsugamushi / genetics*
Phylogeny
Rickettsia / classification*
Rickettsia / genetics*