A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones

Marcelo Isidoro P Reis; Vinícius R Campos; Jackson A L C Resende; Fernando C Silva; Vitor F Ferreira

doi:10.3762/bjoc.11.137

A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones

Beilstein J Org Chem. 2015 Jul 22:11:1235-40. doi: 10.3762/bjoc.11.137. eCollection 2015.

Authors

Marcelo Isidoro P Reis¹, Vinícius R Campos¹, Jackson A L C Resende², Fernando C Silva¹, Vitor F Ferreira¹

Affiliations

¹ Universidade Federal Fluminense, Departamento de Química Orgânica, Campus do Valonguinho, 24020-150, Niterói, RJ, Brazil.
² Universidade Federal Fluminense, Departamento de Química Inorgânica, Campus do Valonguinho, 24020-150, Niterói, RJ, Brazil.

Abstract

A new and efficient method for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones in one step with high yields from the reaction of lawsone with 1,3,5-triazinanes was developed.

Keywords: 1,3,5-triazinane; 1,3-quinazoline; hydrobenzo[g]quinazoline; microwave; naphthoquinone.