Adult granulosa cell tumor presenting with massive ascites, elevated CA-125 level, and low (18)F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography

Obstet Gynecol Sci. 2015 Sep;58(5):423-6. doi: 10.5468/ogs.2015.58.5.423. Epub 2015 Sep 22.

Abstract

Adult granulosa cell tumors (AGCTs) presenting with massive ascites and elevated serum CA-125 levels have rarely been described in the literature. An ovarian mass, massive ascites, and elevated serum CA-125 levels in postmenopausal women generally suggest a malignant ovarian tumor, particularly advanced epithelial ovarian cancer. AGCT has low (18)F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography due to its low metabolic activity. In the present report, we describe a case of an AGCT with massive ascites, elevated serum CA-125 level, and low (18)F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography.

Keywords: 18F-fluorodeoxyglucose; Adult granulosa cell tumor; CA-125; Massive ascites; Positron emission tomography/computed tomography.

Publication types

  • Case Reports