Absent circle of Willis with vascular pollarding in an adult with colpocephaly: A developmental perspective

Neuroradiol J. 2015 Dec;28(6):609-16. doi: 10.1177/1971400915609876. Epub 2015 Oct 6.

Abstract

Absent circle of Willis (COW) has been described in cases of severe forms of cerebral developmental anomalies such as alobar prosencephaly. However, there are no reports of absent COW in patients with a milder form of cerebral abnormality such as colpocephaly. We report a unique case of an adult with colpocephaly and absent COW and discuss their association from a developmental perspective.

Keywords: Absent circle of Willis; brain; colpocephaly; developmental anomalies; magnetic resonance imaging; vascular pollarding.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Basal Ganglia / pathology
  • Brain / pathology
  • Brain Diseases / pathology*
  • Central Nervous System Vascular Malformations / pathology*
  • Circle of Willis / abnormalities*
  • Circle of Willis / pathology*
  • Corpus Callosum / pathology
  • Female
  • Humans
  • Lateral Ventricles / abnormalities*
  • Lateral Ventricles / pathology
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Seizures / etiology
  • Tomography, X-Ray Computed

Supplementary concepts

  • Colpocephaly