Bariatric Surgery in Type 1 Diabetes Mellitus: A Systematic Review

Obes Surg. 2016 Jan;26(1):196-204. doi: 10.1007/s11695-015-1924-z.

Abstract

Bariatric surgery is recognised as an effective treatment strategy for obese patients with type 2 diabetes mellitus. An increasing number of patients with type 1 diabetes mellitus also suffer with obesity and obesity-associated comorbidities but the role of bariatric and metabolic surgery in this group of patients is unclear. This systematic review investigates published English language scientific literature to understand the results of bariatric surgery in obese patients with type 1 diabetes mellitus. We found that these patients can experience significant weight loss and comorbidity resolution with bariatric surgery. Though most patients also see a decline in total insulin requirement, glycaemic control remains difficult. Most of the patients reported in literature have undergone gastric bypass but data is insufficient to recommend any particular procedure.

Keywords: Bariatric surgery; Biliopancreatic diversion; Gastric banding; Gastric bypass; Obesity surgery; Roux-en-Y gastric bypass; Sleeve gastrectomy; Type 1 diabetes mellitus.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Bariatric Surgery*
  • Diabetes Mellitus, Type 1 / complications
  • Diabetes Mellitus, Type 1 / therapy*
  • Dose-Response Relationship, Drug
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Insulin / administration & dosage
  • Obesity / complications
  • Obesity / surgery*
  • Weight Loss

Substances

  • Hypoglycemic Agents
  • Insulin