Effect of Bowel Cleansing on Colonic Transit Time Measurement in Children with Chronic Constipation

Paolo Quitadamo; Nikhil Thapar; Annamaria Staiano; Renato Tambucci; Efstratios Saliakellis; Matilde Pescarin; Chiara Coluccio; Keith J Lindley; Osvaldo Borrelli

doi:10.1016/j.jpeds.2015.09.035

Effect of Bowel Cleansing on Colonic Transit Time Measurement in Children with Chronic Constipation

J Pediatr. 2015 Dec;167(6):1440-2.e1. doi: 10.1016/j.jpeds.2015.09.035. Epub 2015 Oct 9.

Authors

Paolo Quitadamo¹, Nikhil Thapar², Annamaria Staiano³, Renato Tambucci², Efstratios Saliakellis², Matilde Pescarin², Chiara Coluccio², Keith J Lindley², Osvaldo Borrelli⁴

Affiliations

¹ Division of Neurogastroenterology and Motility, Department of Pediatric Gastroenterology, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom; Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy.
² Division of Neurogastroenterology and Motility, Department of Pediatric Gastroenterology, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom.
³ Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy.
⁴ Division of Neurogastroenterology and Motility, Department of Pediatric Gastroenterology, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom. Electronic address: [email protected].

PMID: 26456739
DOI: 10.1016/j.jpeds.2015.09.035

Abstract

We evaluated the effect of bowel preparation on colonic transit time (CTT) measured by the radio-opaque marker test in children with constipation. All children underwent 2 radio-opaque marker-CTT tests, both in cleansed and uncleansed bowel state. Our findings confirm that the state of colonic fecal filling may significantly influence CTT.

MeSH terms

Adolescent
Cathartics / pharmacology*
Child
Child, Preschool
Colon / drug effects
Colon / physiopathology*
Constipation / diagnosis
Constipation / physiopathology*
Female
Gastrointestinal Transit / physiology*
Humans
Isotonic Solutions
Male

Substances

Cathartics
Isotonic Solutions
klean prep