The accuracy of absorbed dose calculations in personalized internal radionuclide therapy is directly related to the accuracy of the activity (or activity concentration) estimates obtained at each of the imaging time points. MIRD Pamphlet no. 23 presented a general overview of methods that are required for quantitative SPECT imaging. The present document is next in a series of isotope-specific guidelines and recommendations that follow the general information that was provided in MIRD 23. This paper focuses on (177)Lu (lutetium) and its application in radiopharmaceutical therapy.
Keywords: SPECT/CT; endocrine; guideline; image processing; lutetium; oncology; quantitative SPECT; radiobiology/dosimetry; radionuclide therapy.
© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.