Pain-related anxiety in relation to anxiety and depression among persons living with HIV/AIDS

AIDS Care. 2016;28(4):432-5. doi: 10.1080/09540121.2015.1100704. Epub 2015 Oct 18.

Abstract

Persons living with HIV/AIDS (PLHA) experience clinically significant pain as a result of HIV and such pain is often related to increased levels of anxiety/depression. Pain-related anxiety has been identified as a mechanism in the onset and progression of pain experience and associated affective distress. However, there has not been empirical study of pain-related anxiety in relation to affective processes among PLHA. To address this gap, hierarchical multiple regressions were conducted using SPSS v.21 to examine pain-related anxiety (as measured using the Pain Anxiety Symptoms Scale) in relation to anxiety and depressive symptoms (as measured using the Mood and Anxiety Symptoms Questionnaire) among 93 PLHA (10.8% female; Mean age = 49.63, SD = 8.89). Pain-related anxiety was significantly related to anxious arousal symptoms (β = .43) and anhedonic depressive symptoms (β = .25); effects were evident beyond the variance accounted for by CD4 count, race, sex, income level, and current level of bodily pain. The present results suggest that pain-related anxiety may play a role in the experience of anxiety and depressive symptoms among PLHA.

Keywords: AIDS; HIV; Pain anxiety; anxiety; depression.

MeSH terms

  • Adult
  • Affect
  • Anxiety / complications
  • Anxiety / psychology*
  • Cross-Sectional Studies
  • Depression / complications
  • Depression / psychology*
  • Female
  • HIV Infections / complications
  • HIV Infections / physiopathology
  • HIV Infections / psychology*
  • Humans
  • Male
  • Middle Aged
  • Pain / psychology*
  • Pain Measurement
  • Psychiatric Status Rating Scales
  • Surveys and Questionnaires