Laboratory guidelines for the diagnosis and follow-up of patients with monoclonal gammopathies

Rev Clin Esp (Barc). 2016 Apr;216(3):128-34. doi: 10.1016/j.rce.2015.09.002. Epub 2015 Oct 17.
[Article in English, Spanish]

Abstract

We present guidelines from the Immunochemistry group of the Spanish Society for Immunology that are designed to provide a practical tool for the diagnosis and follow-up of monoclonal gammopathies. We review the clinical and analytical features of various monoclonal gammopathies, international consensus guidelines and techniques used to detect and follow-up monoclonal components.

Keywords: Amiloidosis; Amyloidosis; Cadenas ligeras; Componente monoclonal; Células plasmáticas; Gammapatía monoclonal; Immunofixation; Immunoglobulins; Inmunofijación; Inmunoglobulinas; Light chains; Mieloma; Monoclonal component; Monoclonal gammopathy; Myeloma; Plasma cells.