We present guidelines from the Immunochemistry group of the Spanish Society for Immunology that are designed to provide a practical tool for the diagnosis and follow-up of monoclonal gammopathies. We review the clinical and analytical features of various monoclonal gammopathies, international consensus guidelines and techniques used to detect and follow-up monoclonal components.
Keywords: Amiloidosis; Amyloidosis; Cadenas ligeras; Componente monoclonal; Células plasmáticas; Gammapatía monoclonal; Immunofixation; Immunoglobulins; Inmunofijación; Inmunoglobulinas; Light chains; Mieloma; Monoclonal component; Monoclonal gammopathy; Myeloma; Plasma cells.
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