We report the case of a 72-year-old woman in whom the sole manifestation of recurrent endometrial adenocarcinoma was a large splenic mass. The clinical presentation mimicked that of malignant lymphoma. Although as many as 9% of carcinomas are associated with splenic metastases, such involvement is typically encountered only at autopsy and associated with widespread extrasplenic metastases. In contrast, we have found only three other reported cases of gynecological malignancy in which a splenic mass was the sole presenting manifestation of recurrent tumor.