A Direct Path to Action Initiation

Christopher H Donahue; Anatol C Kreitzer

doi:10.1016/j.neuron.2015.10.013

A Direct Path to Action Initiation

Neuron. 2015 Oct 21;88(2):240-1. doi: 10.1016/j.neuron.2015.10.013.

Authors

Christopher H Donahue¹, Anatol C Kreitzer²

Affiliations

¹ The Gladstone Institutes, San Francisco, CA, 94158, USA.
² The Gladstone Institutes, San Francisco, CA, 94158, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: [email protected].

PMID: 26494272
DOI: 10.1016/j.neuron.2015.10.013

Abstract

In this issue of Neuron, Sippy et al. (2015) provide the clearest evidence to date that information is differentially encoded in the direct and indirect pathways of the striatum. The results support the classical notion that the direct pathway plays a critical role in initiating actions.

Keywords: action; basal ganglia; direct pathway; indirect pathway.

Publication types

Comment

MeSH terms

Animals
Corpus Striatum / cytology*
Corpus Striatum / physiology*
Goals*
Neurons / physiology*
Psychomotor Performance / physiology*
Reward*