Abstract
Vascular endothelial cells are actively involved in coagulation and inflammation processes and appear to represent an important element in cell-mediated immune responses. In this paper, the possible role of endothelial cells as a target for immunopathological reactions was analyzed. Experimental neurovascular lesions were studied in a model of cerebral malaria, with particular attention to the role of cytokine interactions in vivo.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Animals
-
Biological Factors / physiology*
-
Brain Diseases / pathology
-
Brain Diseases / physiopathology
-
Cytokines
-
Endothelium, Vascular / pathology
-
Endothelium, Vascular / physiopathology*
-
Macrophages / physiology
-
Malaria / pathology
-
Malaria / physiopathology*
-
Mice
-
Plasmodium berghei
-
T-Lymphocytes / physiology
-
Tumor Necrosis Factor-alpha / physiology*
-
Vasculitis / pathology
-
Vasculitis / physiopathology*
Substances
-
Biological Factors
-
Cytokines
-
Tumor Necrosis Factor-alpha