Identification of a novel HLA-C03 variant allele, C03:280 by sequence-based typing

Tissue Antigens. 2015 Dec;86(6):455-6. doi: 10.1111/tan.12685. Epub 2015 Oct 30.

Authors

S Chun¹, J S Song¹, S Yu¹, J S Kim¹, O J Kwon², E S Kang¹

Affiliations

¹ Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
² Biowithus Life Science Institute, Seoul, Korea.

PMID: 26514239
DOI: 10.1111/tan.12685

Abstract

The new allele, HLA-C*03:280 differs from C*03:04:01 by one nucleotide substitution at codon 35 (CGG→CAG).

Keywords: HLA-C*03:280; novel allele; sequence-based typing.

© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Comparative Study

MeSH terms

Adult
Alleles
Amino Acid Substitution
Asian People / genetics
Base Sequence
Exons / genetics
Genes, MHC Class II*
HLA-C Antigens / genetics
HLA-C Antigens / isolation & purification*
Histocompatibility Testing
Humans
Male
Molecular Sequence Data
Republic of Korea
Sequence Alignment
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid

Substances

HLA-C Antigens
HLA-C*03 antigen