Atypical Fast-Slow Atrioventricular Nodal Reentrant Tachycardia Incorporating a "Superior" Slow Pathway: A Distinct Supraventricular Tachyarrhythmia

Circulation. 2016 Jan 12;133(2):114-23. doi: 10.1161/CIRCULATIONAHA.115.018443. Epub 2015 Nov 5.

Abstract

Background: The existence of an atypical fast-slow (F/S) atrioventricular nodal reentrant tachycardia (AVNRT) including a superior (sup) pathway with slow conductive properties and an atrial exit near the His bundle has not been confirmed.

Methods and results: We studied 6 women and 2 men (age, 74 ± 7 years) with sup-F/S-AVNRT who underwent successful radiofrequency ablation near the His bundle. Programmed ventricular stimulation induced retrograde conduction over a superior SP with an earliest atrial activation near the His bundle, a mean shortest spike-atrial interval of 378 ± 119 milliseconds, and decremental properties in all patients. sup-F/S-AVNRT was characterized by a long-RP interval; a retrograde atrial activation sequence during tachycardia identical to that over a sup-SP during ventricular pacing; ventriculoatrial dissociation during ventricular overdrive pacing of the tachycardia in 5 patients or atrioventricular block occurring during tachycardia in 3 patients, excluding atrioventricular reentrant tachycardia; termination of the tachycardia by ATP; and a V-A-V activation sequence immediately after ventricular induction or entrainment of the tachycardia, including dual atrial responses in 2 patients. Elimination or modification of retrograde conduction over the sup-SP by ablation near the right perinodal region or from the noncoronary cusp of Valsalva eliminated and confirmed the diagnosis of AVNRT in 4 patients each.

Conclusions: sup-F/S-AVNRT is a distinct supraventricular tachycardia, incorporating an SP located above the Koch triangle as the retrograde limb, that can be eliminated by radiofrequency ablation.

Keywords: ablation techniques; arrhythmias, cardiac; atrioventricular node; electrophysiology; tachycardia.

Publication types

  • Multicenter Study

MeSH terms

  • Adenosine Triphosphate / pharmacology
  • Aftercare
  • Aged
  • Aged, 80 and over
  • Atrioventricular Node / physiopathology
  • Bundle of His / physiopathology
  • Cardiac Catheterization
  • Cardiac Pacing, Artificial
  • Catheter Ablation
  • Electrocardiography
  • Electrocardiography, Ambulatory
  • Female
  • Heart Conduction System / drug effects
  • Heart Conduction System / physiopathology*
  • Humans
  • Isoproterenol / pharmacology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Tachycardia, Atrioventricular Nodal Reentry / classification
  • Tachycardia, Atrioventricular Nodal Reentry / diagnosis
  • Tachycardia, Atrioventricular Nodal Reentry / physiopathology*
  • Tachycardia, Atrioventricular Nodal Reentry / surgery
  • Tachycardia, Supraventricular / classification
  • Tachycardia, Supraventricular / diagnosis
  • Tachycardia, Supraventricular / physiopathology*
  • Tachycardia, Supraventricular / surgery

Substances

  • Adenosine Triphosphate
  • Isoproterenol