Functional Evaluation of Coronary Disease by CT Angiography

JACC Cardiovasc Imaging. 2015 Nov;8(11):1322-35. doi: 10.1016/j.jcmg.2015.09.003.

Abstract

In recent years, several technical developments in the field of cardiac computed tomography (CT) have made possible the extraction of functional information from an anatomy-based examination. Several different lines have been explored and will be reviewed in the present paper, namely: 1) myocardial perfusion imaging; 2) transluminal attenuation gradients and corrected coronary opacification indexes; 3) fractional flow reserve computed from CT; and 4) extrapolation from atherosclerotic plaque characteristics. In view of these developments, cardiac CT has the potential to become in the near future a truly 2-in-1 noninvasive evaluation for coronary artery disease.

Keywords: cardiac computed tomography; coronary artery disease; functional evaluation.

Publication types

  • Review

MeSH terms

  • Coronary Angiography / methods*
  • Coronary Artery Disease / diagnostic imaging*
  • Coronary Artery Disease / physiopathology
  • Coronary Vessels / diagnostic imaging*
  • Coronary Vessels / physiopathology
  • Female
  • Fractional Flow Reserve, Myocardial*
  • Humans
  • Male
  • Middle Aged
  • Myocardial Perfusion Imaging / methods*
  • Predictive Value of Tests
  • Prognosis
  • Reproducibility of Results
  • Severity of Illness Index
  • Tomography, X-Ray Computed*