Highly Efficient Far Red/Near-Infrared Solid Fluorophores: Aggregation-Induced Emission, Intramolecular Charge Transfer, Twisted Molecular Conformation, and Bioimaging Applications

Hongguang Lu; Yadan Zheng; Xiaowei Zhao; Lijuan Wang; Suqian Ma; Xiongqi Han; Bin Xu; Wenjing Tian; Hui Gao

doi:10.1002/anie.201507031

Highly Efficient Far Red/Near-Infrared Solid Fluorophores: Aggregation-Induced Emission, Intramolecular Charge Transfer, Twisted Molecular Conformation, and Bioimaging Applications

Angew Chem Int Ed Engl. 2016 Jan 4;55(1):155-9. doi: 10.1002/anie.201507031. Epub 2015 Nov 18.

Authors

Hongguang Lu¹, Yadan Zheng², Xiaowei Zhao², Lijuan Wang³, Suqian Ma⁴, Xiongqi Han², Bin Xu⁴, Wenjing Tian⁴, Hui Gao⁵

Affiliations

¹ Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384 (P. R. China). [email protected].
² Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384 (P. R. China).
³ School of materials science and engineering, Harbin Institute of Technology at Weihai, Weihai 264209 (P. R. China).
⁴ State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012 (P. R. China).
⁵ Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384 (P. R. China). [email protected].

PMID: 26576818
DOI: 10.1002/anie.201507031

Abstract

The development of organic fluorophores with efficient solid-state emissions or aggregated-state emissions in the red to near-infrared region is still challenging. Reported herein are fluorophores having aggregation-induced emission ranging from the orange to far red/near-infrared (FR/NIR) region. The bioimaging performance of the designed fluorophore is shown to have potential as FR/NIR fluorescent probes for biological applications.

Keywords: aggregation; fluorescent probes; imaging agents; luminescence; materials science.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Line, Tumor
Fluorescent Dyes / chemistry*
Fluorescent Dyes / radiation effects*
Humans
Infrared Rays*
Mice
Molecular Conformation / radiation effects
Molecular Imaging / methods*

Substances

Fluorescent Dyes