Lipidated APOE has effects on cognitive function that are independent of amyloid-β pathology

Angela Corona; Gary Landreth

doi:10.1093/brain/awv300

Lipidated APOE has effects on cognitive function that are independent of amyloid-β pathology

Brain. 2015 Dec;138(Pt 12):3470-2. doi: 10.1093/brain/awv300.

Authors

Angela Corona¹, Gary Landreth²

Affiliations

¹ Alzheimer Research Laboratory, Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland.
² Alzheimer Research Laboratory, Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland [email protected].

Abstract

This scientific commentary refers to ‘Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice’, by Fitz et al. (doi:10.1093/brain/awv293).

Publication types

Comment

MeSH terms

Amyloid beta-Protein Precursor / genetics*
Animals
Apolipoprotein A-I / deficiency*
Apolipoproteins E / deficiency*
Cognition Disorders / genetics*
Cognition Disorders / psychology*
Female
Gene Deletion*
Male
Plaque, Amyloid / genetics*

Substances

Amyloid beta-Protein Precursor
Apolipoprotein A-I
Apolipoproteins E

Abstract

Publication types

MeSH terms

Substances

Grants and funding